Introduction of early health technology assessment for innovators, clinicians, and funders

Document

Introduction of early health technology assessment for innovators, clinicians, and funders

June 24, 2026

Teerawat Wiwatpanit, Yot Teerawattananon & Yi Wang

Date

June 19, 2026

Abstract

Health technology faces rising costs, system complexities, and gaps between development and coverage policies, limiting translation into practice. Traditional health technology assessment (HTA) evaluates technologies at late stages, providing little support if a technology fails to secure reimbursement. Early HTA addresses this by assessing technologies during research and development stages, helping innovators prioritise disease areas, define target product profiles, and establish value propositions. Early HTA could reduce development risks and uncertainties and inform development choices that could improve cost-effectiveness and enhance long-term viability, adaptability, and adoptability in the healthcare system.

Acknowledgements

This work was supported by Thailand Science Research and Innovation (TSRI), Thailand. Contract number: FFB670043/0401.

Link to original publication: https://www.nature.com/articles/s44401-026-00102-2

TagsEarly HTA

Related Document

August 30, 2020

Guidance on use of modelling for policy responses to COVID-19

By HITAP

As COVID-19 spreads worldwide, national (and sub-national) governments and development partners are making use of a rapidly growing body of evidence to develop policies mitigating against this devastating pandemic. Mathematical models and computational simulation models play a unique role to inform resource planning and policy development (among other uses) through scenario analysis and short-term forecasting. Already in the first six months of this outbreak, we have seen many models at the sub-national, national, regional and global level being developed at an impressive speed.

June 30, 2023

Factsheet: ทำความรู้จัก Early HTA การประเมินที่จะทำให้งานวิจัยพัฒนานวัตกรรมไม่สูญเปล่า

โดย HITAP

ชวนทำความรู้จัก Early HTA การประเมินที่จะทำให้งานวิจัยพัฒนานวัตกรรมไม่สูญเปล่า นวัตกรรมด้านสุขภาพต้องดีแค่ไหนถึงจะเป็นที่ต้องการของผู้ใช้หรือขายได้? ทำอย่างไรถึงจะรู้ได้ว่าควรลงทุนวิจัยและพัฒนานวัตกรรม นั้นไหม? Early HTA มีคำตอบ! การประเมินเทคโนโลยีด้านสุขภาพในระยะพัฒนานวัตกรรม หรือ early HTA ทำให้ผู้ลงทุนและผู้พัฒนานวัตกรรมทราบเป้าหมาย คุณลักษณะหรือคุณสมบัติของเทคโนโลยีที่ต้องพัฒนาขึ้น เพื่อให้เทคโนโลยีนั้น ๆ เป็นที่ต้องการสูงสุดของตลาด

April 26, 2021

A Cost Analysis of Key Population Interventions to Fast Track the End of the HIV Epidemic in Thailand

By HITAP

This report also includes an in-depth discussion of factors and variables that affect unit costs, including labor (the most prominent), fixed costs, and potential contribution to epidemic control (e.g. achievement of targets). Key factors impacting input costs include staffing number and type, and capital costs, output costs vary based on factors including number and type of activities, innovations, and capacity to achieve targets. However, assessment of technical efficiency by model and site posed challenges. Assessed sites provide different activities along the services cascade depending on KP group, geographical location, and other contextual factors. This variation also makes it difficult to determine specific drivers of unit costs. In addition, differenced in number and type of program inputs and outputs for activities result in variations in unit costs.

August 17, 2018

Executive Summary: Monitoring and evaluation of Thailand’s global health initiatives

By HITAP

The Thai government introduced its first Global Health Strategic Framework for 2016 to 2020 in 2016, under the cooperation between the Ministry of Public Health, Ministry of Foreign Affairs, and other sectors involved in global health initiatives. This was to promote policy coherence across sectors and enhance the country's health security, which can contribute to sustainable economic and social development. It also aimed at enabling Thailand to play a leading role in global health policy issues. In order to accomplish the goals of the global health strategic framework and effectively implement the strategy, the development of a monitoring & evaluation (M&E) mechanism is required as a tool to monitor progress and evaluate outputs of the plan. This study aimed to review monitoring and evaluation mechanisms and frameworks implemented in other countries. Information obtained from this review will be used to support the development of an M&E mechanism and framework for the Thai global health strategic framework. Researchers employed descriptive literature search and review to obtain the required data. The review results were grouped into two categories: 1) M&E mechanisms implemented in seven countries, namely Australia, Canada, Japan, Norway, Switzerland, the UK, and the USA; and 2) case studies of M&E frameworks used to evaluate three global health issues, i.e. communicable disease surveillance, prevention and control of HIV/TB, and health systems strengthening, which were developed and promoted by the World Health Organization, Global Fund, and their partner organizations.